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MYP_071660
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Basic Information
Galaxamide [MeLeu2,4P]
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Enzyme modulation ▸ Enzyme inhibition ▸ DPP-IV inhibition ▸ DPP-IV inhibitory
Metabolic ▸ Glucose metabolism ▸ Antidiabetic
Other / Curated residual function label ▸ Generic enzyme inhibition annotation
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
5 amino acids
C28H49N5O6
Standard
Sequence
LPLPL
Physicochemical Analysis
551.72 Da
5.53
-0.24
-0.44
-0.0480
1.64
0.19
0.68
85.04
234.00
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
162.14
1.49
4.0
6.0
13.0
39.0
2.0
4.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0002463 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
head-to-tail cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
PMID35323457 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35323457/
RECORD: Rec_0030108 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
beta-Casein-derived
9913
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
DPP-IV inhibitory Antidiabetic
Dipeptidyl peptidase-IV (DPP-IV)
325 μM
IC50
PaperSusceptibility of milk protein-derived peptides to dipeptidyl peptidase IV (DPP-IV) hydrolysis | Nongonierma, A. et al. | DOI: 10.1016/j.foodchem.2013.08.097 Evidence URLhttps://www.uniprot.org/uniprotkb/P02666/entry
RECORD: Rec_0047261 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
DPP-IV Inhibitory
DPP-IV
RECORD: Rec_0170906 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
head-to-tail cyclic peptide [Cyclic]
mixed L/D amino-acid peptide [Mixed]
None
None
Bio-Activity Profile
Antimicrobial Anticancer
PMID35323457 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35323457/
RECORD: Rec_0214522 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
head-to-tail cyclic peptide [Cyclic]
mixed L/D amino-acid peptide [Mixed]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
PMID35323457 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35323457/
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