Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length102 amino acids

Chemical FormulaC499H801N141O151S12

DescriptionStandard

        MSVMKPCLMTIAIFMILAQKTPGGLFRSHNGKSREPWNPCELYQGMCRNTCRKYEIQYLTCPNDQKCCLKLSVKITSSKNVKENYDSNSNLSVANSSSYSHI
    

Molecular Weight11576.33 Da

Isoelectric Point (pI)9.17

Net Charge (pH 7.0)6.60

Net Charge (pH 7.4) 6.16

Charge Density (pH 7.0) 0.0648

GRAVY Index-0.44

Hydrophobic Moment 0.55

Boman Index-0.07

Instability Index41.13

Aliphatic Index 67.84

Aromaticity 0.0784

Extinction Coeff. Reduced 12950.00

Extinction Coeff. Oxidized 13325.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4762.66

LogP -54.73

H-bond Donors 171.0

H-bond Acceptors 172.0

Rotatable Bonds 388.0

Heavy Atoms 803.0

Ring Count 16.0

Amide Bonds 114.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0173679 VERIFIED: NO

Provenance & Taxonomy

OrganismMacaca fascicularis [Animal]

FamilyDefensin

Tax ID9541

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence