Peptide Database

Peptide NameAgitoxin 2

Function Ontology

Annotation / Sequence feature ▸ Nuclear export signal

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Host defense activity

Membrane / Ion-channel modulation ▸ Ion channel inhibition

Membrane / Ion-channel modulation ▸ Potassium channel modulation ▸ Potassium channel inhibitor

Venom / Toxin ▸ General toxin ▸ Toxin

Venom / Toxin ▸ Toxin

Standard StatusStandard

Sequence Length38 amino acids

Chemical FormulaC169H284N54O48S8

DescriptionStandard

        GVPINVSCTGSPQCIKPCKDAGMRFGKCMNRKCHCTPK
    

Molecular Weight4096.92 Da

Isoelectric Point (pI)9.34

Net Charge (pH 7.0)5.78

Net Charge (pH 7.4) 5.43

Charge Density (pH 7.0) 0.1522

GRAVY Index-0.42

Hydrophobic Moment 0.72

Boman Index-0.12

Instability Index59.69

Aliphatic Index 38.42

Aromaticity 0.0263

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 375.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1634.93

LogP -20.99

H-bond Donors 61.0

H-bond Acceptors 63.0

Rotatable Bonds 134.0

Heavy Atoms 279.0

Ring Count 6.0

Amide Bonds 40.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0178224 VERIFIED: NO

Provenance & Taxonomy

OrganismLeiurus quinquestriatus [Animal]

Structure & Mods

Configlinear disulfide-stabilized peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide8-28, 14-33, 18-35

Bio-Activity Profile

Function

Toxin

RECORD: Rec_0294444 VERIFIED: YES

Provenance & Taxonomy

OrganismLeiurus quinquestriatus hebraeus [Animal]

FamilyPotassium channel inhibitor family

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide8-28; 14-33; 18-35

Bio-Activity Profile

Function

Toxin Venom Potassium channel inhibitor family Ion channel inhibitor Pathogenesis-associated Host defense