Peptide Database

Peptide NameDEFENSIN domain-containing protein

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Fungicidal activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length94 amino acids

Chemical FormulaC446H716N134O143S7

DescriptionStandard

        MRTLAILAAILLFALQAQAESLQERADEAATQEQPGEDDQDLAVSFEENGLSTLRASGSQARRTCYCRTGRCYTPEFHSGKCLFKGRTYKLCCR
    

Molecular Weight10467.72 Da

Isoelectric Point (pI)6.55

Net Charge (pH 7.0)-0.45

Net Charge (pH 7.4) -0.83

Charge Density (pH 7.0) -0.0048

GRAVY Index-0.42

Hydrophobic Moment 0.56

Boman Index-0.12

Instability Index41.80

Aliphatic Index 69.79

Aromaticity 0.0745

Extinction Coeff. Reduced 4470.00

Extinction Coeff. Oxidized 4845.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4531.88

LogP -53.18

H-bond Donors 166.0

H-bond Acceptors 151.0

Rotatable Bonds 353.0

Heavy Atoms 730.0

Ring Count 10.0

Amide Bonds 101.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0201202 VERIFIED: NO

Provenance & Taxonomy

OrganismMandrillus leucophaeus [Animal]

FamilyDefensin

Tax ID9568

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Antifungal Fungicide Non-hemolytic

MethodQualitative functional evidence