Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length264 amino acids

Chemical FormulaC1293H2092N354O363S8

DescriptionStandard

        MAREPDSALRWAALLVLATLGTAVMAATNPGVVARITQKGLDYACQQGVAVLQKELEKINIPDFSGSFKIKHLGKGHYSFYSMVIRGFQLPSSQIRLVPNKGLDLSIRNANVKISGKWKARKKFIKIKGNFDLGVEGISISAGLELGFDPASGLPTATCSSCSNHIKSVSVRISGGKLGWLIQLFHKKIESSFRKTMASKICQIVTSSVSSKLQSYLKTLRVTTKIDKVSGINYSLVAAPTATANNLDWQLKNFLLFGADVHYG
    

Molecular Weight28661.12 Da

Isoelectric Point (pI)9.99

Net Charge (pH 7.0)19.89

Net Charge (pH 7.4) 19.30

Charge Density (pH 7.0) 0.0754

GRAVY Index0.04

Hydrophobic Moment 0.69

Boman Index0.09

Instability Index32.61

Aliphatic Index 99.02

Aromaticity 0.0795

Extinction Coeff. Reduced 30940.00

Extinction Coeff. Oxidized 31190.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0056032 VERIFIED: NO

Provenance & Taxonomy

OrganismLeptonychotes weddellii (Weddell seal) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria