Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length336 amino acids

Chemical FormulaC1739H2775N447O486S11

DescriptionStandard

        MIVAQNNRGDLLVSVQNCQLSTGNIEVQLNSEGRWYYNAFVQHLEKVIRTRLESQLCLNVILRIQKEAEVLKELKGVFQINPFVQVKYSLITPPEVFKSYVDLDFKVSVYFSRNHTESPFVAAPFALPEKNNYMLFSGISESLLNSITLTYYTTRVSKVTFSEEHSSYFNLTTDTLSRVIPQVMQHYTKSHPVRMKLMVTAAPVLRLKNNSFTIEIPCFVVVSALLSNSMIKPIFAVNASIGLKAKAVIAKQKLIVLMQLQRLYLSLTYSSIGSFQAQRLKNFLSYSLQNTVIPPIAAALKRGLQLPTMAKLFLSEAVTEVNKGYILISTDLNYKY
    

Molecular Weight38073.05 Da

Isoelectric Point (pI)9.59

Net Charge (pH 7.0)13.92

Net Charge (pH 7.4) 13.32

Charge Density (pH 7.0) 0.0414

GRAVY Index0.12

Hydrophobic Moment 0.78

Boman Index0.11

Instability Index34.36

Aliphatic Index 107.86

Aromaticity 0.1012

Extinction Coeff. Reduced 29340.00

Extinction Coeff. Oxidized 29465.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0131754 VERIFIED: NO

Provenance & Taxonomy

OrganismLaticauda laticaudata [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria

MethodQualitative functional evidence