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MYP_071502
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Basic Information
Esculentin-2CHa [C31S, C37S]
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
37 amino acids
C173H289N47O49
Standard
Sequence
GFSSIFRGVAKFASKGLGKDLAKLGVDLVASKISKQS
Physicochemical Analysis
3811.43 Da
10.30
4.76
4.54
0.1285
0.19
0.75
0.09
17.66
97.57
0.0811
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1568.01
-16.73
56.0
54.0
135.0
269.0
3.0
37.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0201626 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
Esculentin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
PMID23159562 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23159562/
RECORD: Rec_0232621 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Esculentin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus ATCC 25923
25 μM
MIC
PMID23159562 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23159562/
RECORD: Rec_0243100 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Esculentin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Stenotrophomonas maltophilia B32/4
6 μM
MIC
PMID23159562 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23159562/
RECORD: Rec_0275060 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Esculentin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Stenotrophomonas maltophilia B32/1
12.5 μM
MIC
PMID23159562 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23159562/
RECORD: Rec_0278832 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Esculentin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus 145/08
100 μM
MIC
PMID23159562 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23159562/
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