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MYP_071502
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Basic Information
Esculentin-2CHa [C31S, C37S]
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
37 amino acids
C173H289N47O49
Standard
Sequence
GFSSIFRGVAKFASKGLGKDLAKLGVDLVASKISKQS
Physicochemical Analysis
3811.43 Da
10.30
4.76
4.54
0.1285
0.19
0.75
0.09
17.66
97.57
0.0811
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1568.01
-16.73
56.0
54.0
135.0
269.0
3.0
37.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0062669 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Esculentin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
human erythrocytes
>200 μM
Hemolysis
PMID23159562 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23159562/
RECORD: Rec_0124286 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
Esculentin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
Human erythrocytes
>200 μM
Hemolysis
PMID23159562 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23159562/
RECORD: Rec_0147681 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Esculentin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Acinetobacter baumannii NM8
12.5 μM
MIC
PMID23159562 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23159562/
RECORD: Rec_0152785 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Esculentin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Human lung carcinoma A549
26 μM
LC50
PMID23159562 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23159562/
RECORD: Rec_0173462 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Esculentin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus 127/08
50 μM
MIC
PMID23159562 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23159562/
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