Peptide Database

Peptide NameUnnamed

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Standard StatusStandard

Sequence Length42 amino acids

Chemical FormulaC204H335N73O52S6

DescriptionStandard

        EGVRNHVTCRINRGFCVPIRCPGRTRQIGTCFGPRIKCCRSW
    

Molecular Weight4834.69 Da

Isoelectric Point (pI)10.63

Net Charge (pH 7.0)7.86

Net Charge (pH 7.4) 7.55

Charge Density (pH 7.0) 0.1872

GRAVY Index-0.39

Hydrophobic Moment 0.76

Boman Index-0.22

Instability Index25.24

Aliphatic Index 57.86

Aromaticity 0.0714

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5875.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2043.23

LogP -23.89

H-bond Donors 81.0

H-bond Acceptors 67.0

Rotatable Bonds 155.0

Heavy Atoms 335.0

Ring Count 8.0

Amide Bonds 44.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0310375 VERIFIED: YES

Provenance & Taxonomy

OrganismBos taurus [Animal]

FamilyDefensin

Tax ID9913

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitystereochemistry not specified [Other]

DisulfideDisulfide bond(s) reported

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative

TargetStaphylococcus aureus 502A

Activity10-300 μg/mL

MethodMIC

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