Peptide Database

Peptide NameCTR-S domain

Function Ontology

Enzyme modulation ▸ Enzyme inhibition ▸ Complement inhibition

Standard StatusStandard

Sequence Length124 amino acids

Chemical FormulaC649H964N166O219S2

DescriptionStandard

        DIRCKDDEFTHLYTLIVRPDNTYEVKIDNSQVESGSLEDDWDFLPPKKIKDPDAAKPEDWDERAKIDDPTDSKPEDWDKPEHIPDPDAKKPEDWDEEMDGEWEPPVIQNPEYKGEWKPRQIDNP
    

Molecular Weight14659.71 Da

Isoelectric Point (pI)4.21

Net Charge (pH 7.0)-21.02

Net Charge (pH 7.4) -21.41

Charge Density (pH 7.0) -0.1695

GRAVY Index-1.53

Hydrophobic Moment 0.54

Boman Index-0.28

Instability Index25.60

Aliphatic Index 50.32

Aromaticity 0.0887

Extinction Coeff. Reduced 37470.00

Extinction Coeff. Oxidized 37470.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6181.50

LogP -54.02

H-bond Donors 199.0

H-bond Acceptors 202.0

Rotatable Bonds 473.0

Heavy Atoms 1036.0

Ring Count 35.0

Amide Bonds 130.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0044654 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

It binds to C1q Complement inhibition

MethodRadioactivity measured with a gamma counter

Half-LifeRat plasma, in vivo; 72.6 s