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MYP_071409
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Basic Information
HYL-22
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
16 amino acids
C88H157N23O19
Standard
Sequence
GKLSSLWKKLKKIIAK
Physicochemical Analysis
1841.33 Da
10.70
5.75
5.54
0.3596
-0.26
0.71
-0.09
9.68
128.12
0.0625
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
712.19
-2.97
26.0
25.0
69.0
130.0
2.0
15.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0376218 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal Hemolytic
PaperAntimicrobial Peptide from the Wild Bee Hylaeus signatus Venom and Its Analogues: Structure-Activity Study and Synergistic Effect with Antibiotics PMID26998557 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26998557/
RECORD: Rec_0404731 VERIFIED: YES
Provenance & Taxonomy
Hylaeus signatus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Hemolytic
Human RBCs
400 μM
LC50
PMID26998557 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26998557/
RECORD: Rec_0407820 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Pseudomonas aeruginosa 5482
6.8 μM
MIC
PaperAntimicrobial Peptide from the Wild Bee Hylaeus signatus Venom and Its Analogues: Structure-Activity Study and Synergistic Effect with Antibiotics PMID26998557 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26998557/
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