Peptide Database

Peptide NameMu-agatoxin-Hc1c (Mu-AGTX-Hc1c; CT-III; Curtatoxin-3)

Function Ontology

Insecticidal/Pest control ▸ Insecticidal activity

Venom / Toxin ▸ General toxin ▸ Toxin

Standard StatusStandard

Sequence Length38 amino acids

Chemical FormulaC174H252N50O57S9

DescriptionStandard

        ADCVGDGQKCADWFGPYCCSGYYCSCRSMPYCRCRSDS
    

Molecular Weight4244.75 Da

Isoelectric Point (pI)6.08

Net Charge (pH 7.0)-0.28

Net Charge (pH 7.4) -0.60

Charge Density (pH 7.0) -0.0075

GRAVY Index-0.46

Hydrophobic Moment 0.44

Boman Index-0.10

Instability Index50.40

Aliphatic Index 12.89

Aromaticity 0.1579

Extinction Coeff. Reduced 11460.00

Extinction Coeff. Oxidized 11960.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1724.31

LogP -22.43

H-bond Donors 70.0

H-bond Acceptors 66.0

Rotatable Bonds 129.0

Heavy Atoms 290.0

Ring Count 9.0

Amide Bonds 38.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0150690 VERIFIED: YES

Provenance & Taxonomy

OrganismHololena curta [Animal]

Structure & Mods

Configtopology not specified [Not included yet]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Insecticidal

Targetdomestica

Activity4 μg/g

MethodLD50

RECORD: Rec_0388940 VERIFIED: NO

Provenance & Taxonomy

OrganismHololena curta [Animal]

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Disulfide3-19; 10-24; 18-34; 26-32

Bio-Activity Profile

Function

Toxin