Peptide Database

Peptide NameiAβ5p-A1

Function Ontology

beta-sheet breaker peptides

Standard StatusStandard

Sequence Length5 amino acids

Chemical FormulaC25H42N6O9S

DescriptionStandard

        LPNME
    

Molecular Weight602.70 Da

Isoelectric Point (pI)4.60

Net Charge (pH 7.0)-1.23

Net Charge (pH 7.4) -1.44

Charge Density (pH 7.0) -0.2464

GRAVY Index-0.58

Hydrophobic Moment 0.33

Boman Index0.06

Instability Index46.52

Aliphatic Index 78.00

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 251.32

LogP -1.62

H-bond Donors 7.0

H-bond Acceptors 9.0

Rotatable Bonds 18.0

Heavy Atoms 41.0

Ring Count 1.0

Amide Bonds 5.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0335247 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyAmyloid-beta

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitymixed L/D amino-acid peptide [Mixed]

N-TermAcetylation

C-TermAmidation

Other ModsNMe

Bio-Activity Profile

Function

beta-sheet breaker peptides

MethodRP-HPLC

Half-LifeHuman plasma, in vitro; >86400 s