‹ ›
MYP_071318
← PREVIOUS NEXT → BACK
Basic Information
Ocellatin-F1, OF1 (Fallaxin) [Cleaved into: Fallaxin(1-22) (Ocellatin-LB1) ]
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibiotic activity
Antimicrobial ▸ Antifungal
Antimicrobial ▸ Antifungal ▸ Anti-Candida
Antiviral
Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
25 amino acids
C113H198N32O32S
Standard
Sequence
GVVDILKGAAKDIAGHLASKVMNKL
Physicochemical Analysis
2549.04 Da
9.53
1.85
1.58
0.0738
0.43
0.59
0.18
3.78
128.80
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1032.40
-8.74
35.0
36.0
90.0
178.0
1.0
25.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0284110 VERIFIED: YES
Provenance & Taxonomy
Leptodactylus fallax [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative Hemolytic
PMID15544856 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15544856/
RECORD: Rec_0300626 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0301532 VERIFIED: YES
Provenance & Taxonomy
Leptodactylus fallax [Animal]
Fallaxin
Structure & Mods
ribosomal mature linear peptide [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial
PaperS.L. Nielsen et al. / Protein Science 16 (2007) 1969-1976. Structure-activity study of the antibacterial peptide fallaxin
RECORD: Rec_0305930 VERIFIED: YES
Provenance & Taxonomy
Leptodactylus fallax [Animal]
Frog skin active peptide (FSAP); Ocellatin subfamily
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Defense peptide Antimicrobial Antibiotic Antiviral Antifungal Anti-Candida Anti-Gram-negative Anti-Gram-positive Hemolytic
Staphylococcus aureus (Gram-positive)
PMID15544856 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15544856/
RECORD: Rec_0319712 VERIFIED: YES
Provenance & Taxonomy
Leptodactylus fallax [Animal]
Ocellatin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Refer PubMed: 28115922 Aggregatibacter actinomycetemcomitans 29522
24.84 μM
MIC
PMID15544856;28115922 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15544856/
FIRST PREV 1 ... 4 5 6 7 8 NEXT LAST
Showing 5 records on this page · Page 6 of 8