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MYP_071318
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Basic Information
Ocellatin-F1, OF1 (Fallaxin) [Cleaved into: Fallaxin(1-22) (Ocellatin-LB1) ]
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibiotic activity
Antimicrobial ▸ Antifungal
Antimicrobial ▸ Antifungal ▸ Anti-Candida
Antiviral
Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
25 amino acids
C113H198N32O32S
Standard
Sequence
GVVDILKGAAKDIAGHLASKVMNKL
Physicochemical Analysis
2549.04 Da
9.53
1.85
1.58
0.0738
0.43
0.59
0.18
3.78
128.80
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1032.40
-8.74
35.0
36.0
90.0
178.0
1.0
25.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0246205 VERIFIED: YES
Provenance & Taxonomy
Leptodactylus fallax [Animal]
Fallaxin
Structure & Mods
ribosomal mature linear peptide [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Escherichia coli
40.0 μM
MIC
PaperL.A. Rollins-Smith et al. / Regulatory Peptides 124 (2005) 173-178. An antimicrobial peptide from the skin secretions of the mountain chicken frog Leptodactylus fallax (Anura:Leptodactylidae)
RECORD: Rec_0253224 VERIFIED: YES
Provenance & Taxonomy
Leptodactylus fallax [Animal]
Ocellatin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus
PMID15544856;28115922 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15544856/
RECORD: Rec_0253682 VERIFIED: YES
Provenance & Taxonomy
Leptodactylus fallax [Animal]
Ocellatin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Candida albicans
PMID15544856;28115922 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15544856/
RECORD: Rec_0258546 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct based on Indian mountain chick [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
C. lusitaniae
50.25 μM
MIC
PaperAn antimicrobial peptide from the skin secretions of the mountain chicken frog Leptodactylus fallax (Anura:Leptodactylidae).
RECORD: Rec_0279476 VERIFIED: YES
Provenance & Taxonomy
Leptodactylus fallax [Animal]
Ocellatin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Pseudomonas aeruginosa
PMID15544856;28115922 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15544856/
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