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MYP_071318
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Basic Information
Ocellatin-F1, OF1 (Fallaxin) [Cleaved into: Fallaxin(1-22) (Ocellatin-LB1) ]
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibiotic activity
Antimicrobial ▸ Antifungal
Antimicrobial ▸ Antifungal ▸ Anti-Candida
Antiviral
Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
25 amino acids
C113H198N32O32S
Standard
Sequence
GVVDILKGAAKDIAGHLASKVMNKL
Physicochemical Analysis
2549.04 Da
9.53
1.85
1.58
0.0738
0.43
0.59
0.18
3.78
128.80
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1032.40
-8.74
35.0
36.0
90.0
178.0
1.0
25.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0173395 VERIFIED: YES
Provenance & Taxonomy
Leptodactylus fallax [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Pseudomonas aeruginosa
80 μM
MIC
PMID15544856 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15544856/
RECORD: Rec_0174091 VERIFIED: YES
Provenance & Taxonomy
Leptodactylus fallax [Animal]
Ocellatin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Refer PubMed: 28115922 Aggregatibacter actinomycetemcomitans 29522
109.91 μM
MIC
PMID15544856;28115922 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15544856/
RECORD: Rec_0230894 VERIFIED: YES
Provenance & Taxonomy
Leptodactylus fallax [Animal]
Ocellatin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Refer PubMed: 28115922 Aggregatibacter actinomycetemcomitans 29522
397.45 μM
MIC
PMID15544856;28115922 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15544856/
RECORD: Rec_0232579 VERIFIED: YES
Provenance & Taxonomy
Leptodactylus fallax [Animal]
Frog skin active peptide (FSAP); Ocellatin subfamily
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Defense peptide Antimicrobial Antibiotic Antiviral Antifungal Anti-Candida Anti-Gram-negative Anti-Gram-positive Hemolytic
K. pneumoniae (Gram-negative)
PMID15544856 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15544856/
RECORD: Rec_0235750 VERIFIED: NO
Provenance & Taxonomy
Leptodactylus labyrinthicus [Animal]
Ocellatin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PMID26635873;28115922;29596881 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26635873/
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