Peptide Database

Peptide NameOcellatin-F1, OF1 (Fallaxin) [Cleaved into: Fallaxin(1-22) (Ocellatin-LB1) ]

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Anti-Candida

Antiviral

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Venom / Toxin ▸ General toxin ▸ Toxic

Standard StatusStandard

Sequence Length25 amino acids

Chemical FormulaC113H198N32O32S

DescriptionStandard

        GVVDILKGAAKDIAGHLASKVMNKL
    

Molecular Weight2549.04 Da

Isoelectric Point (pI)9.53

Net Charge (pH 7.0)1.85

Net Charge (pH 7.4) 1.58

Charge Density (pH 7.0) 0.0738

GRAVY Index0.43

Hydrophobic Moment 0.59

Boman Index0.18

Instability Index3.78

Aliphatic Index 128.80

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1032.40

LogP -8.74

H-bond Donors 35.0

H-bond Acceptors 36.0

Rotatable Bonds 90.0

Heavy Atoms 178.0

Ring Count 1.0

Amide Bonds 25.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0113726 VERIFIED: YES

Provenance & Taxonomy

OrganismLeptodactylus fallax [Animal]

FamilyFrog skin active peptide (FSAP); Ocellatin subfamily

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Defense peptide Antimicrobial Antibiotic Antiviral Antifungal Anti-Candida Anti-Gram-negative Anti-Gram-positive Hemolytic

TargetE. cloacae (Gram-negative)

RECORD: Rec_0126942 VERIFIED: YES

Provenance & Taxonomy

OrganismLeptodactylus fallax [Animal]

FamilyOcellatin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative

TargetKlebsiella pneumoniae

RECORD: Rec_0127423 VERIFIED: YES

Provenance & Taxonomy

OrganismLeptodactylus fallax [Animal]

FamilyOcellatin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative

TargetRefer PubMed: 28115922 Aggregatibacter actinomycetemcomitans 29522

Activity50.25 μM

MethodMIC

RECORD: Rec_0154435 VERIFIED: YES

Provenance & Taxonomy

OrganismLeptodactylus fallax [Animal]

FamilyOcellatin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative

TargetEnterobacter cloacae

RECORD: Rec_0154720 VERIFIED: YES

Provenance & Taxonomy

OrganismLeptodactylus fallax [Animal]

FamilyFrog skin active peptide (FSAP); Ocellatin subfamily

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Defense peptide Antimicrobial Antibiotic Antiviral Antifungal Anti-Candida Anti-Gram-negative Anti-Gram-positive Hemolytic

TargetEscherichia coli (Gram-negative)

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