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MYP_071271
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Basic Information
Darobactin B
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
7 amino acids
C51H68N14O10
Standard
Sequence
WNWTKRF
Physicochemical Analysis
1037.17 Da
11.00
1.76
1.55
0.2513
-1.66
0.66
-0.29
36.49
0.00
0.4286
11000.00
11000.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
420.74
-1.35
16.0
12.0
30.0
75.0
5.0
7.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0370533 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Acinetobacter baumannii AB057
32 μg/mL
MIC
PMID34937193 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/34937193/
RECORD: Rec_0379922 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli AR350
4 μg/mL
MIC
PMID34937193 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/34937193/
RECORD: Rec_0400381 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus HG003
128 μg/mL
MIC
PMID34937193 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/34937193/
RECORD: Rec_0423770 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Darobactin-resistant Escherichia coli MG1655 mutant strain 3
128 μg/mL
MIC
PMID34937193 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/34937193/
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