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MYP_071271
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Basic Information
Darobactin B
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
7 amino acids
C51H68N14O10
Standard
Sequence
WNWTKRF
Physicochemical Analysis
1037.17 Da
11.00
1.76
1.55
0.2513
-1.66
0.66
-0.29
36.49
0.00
0.4286
11000.00
11000.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
420.74
-1.35
16.0
12.0
30.0
75.0
5.0
7.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0326793 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Salmonella enterica ATCC 13076
1 μg/mL
MIC
PMID34937193 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/34937193/
RECORD: Rec_0349389 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Bacteroides fragilis ATCC 25285
128 μg/mL
MIC
PMID34937193 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/34937193/
RECORD: Rec_0352457 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Darobactin-resistant Escherichia coli MG1655 mutant strain 2
128 μg/mL
MIC
PMID34937193 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/34937193/
RECORD: Rec_0358209 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli MMGI1
1 μg/mL
MIC
PMID34937193 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/34937193/
RECORD: Rec_0365192 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Klebsiella pneumoniae DSM30104
1
MIC
PMID34937193 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/34937193/
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