‹ ›
MYP_071271
← PREVIOUS NEXT → BACK
Basic Information
Darobactin B
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
7 amino acids
C51H68N14O10
Standard
Sequence
WNWTKRF
Physicochemical Analysis
1037.17 Da
11.00
1.76
1.55
0.2513
-1.66
0.66
-0.29
36.49
0.00
0.4286
11000.00
11000.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
420.74
-1.35
16.0
12.0
30.0
75.0
5.0
7.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0063151 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Darobactin-resistant Escherichia coli MG1655 mutant strain 1
128 μg/mL
MIC
PMID34937193 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/34937193/
RECORD: Rec_0069190 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Pseudomonas aeruginosa PA14
8 μg/mL
MIC
PMID34937193 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/34937193/
RECORD: Rec_0086486 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli ATCC 25922
2 μg/mL
MIC
PMID34937193 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/34937193/
RECORD: Rec_0086552 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Acinetobacter baumannii LAC-4
4 μg/mL
MIC
PMID34937193 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/34937193/
RECORD: Rec_0117719 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
PMID34937193 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/34937193/
FIRST PREV 1 2 3 4 ... 7 NEXT LAST
Showing 5 records on this page · Page 2 of 7