Peptide Database

Peptide NameCircular bacteriocin; circularin A uberolysin family

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length108 amino acids

Chemical FormulaC524H874N132O136S3

DescriptionStandard

        MVATRNEIKLSLLLGALAMGFLMLALFLFSLQFLPVADLAKEFGIPASIAAVVLNIVNAGGAVTTIVSILLAVGSGGLSLLAAAGKETIRQFLKKKIQEKGKRATIAW
    

Molecular Weight11295.54 Da

Isoelectric Point (pI)10.21

Net Charge (pH 7.0)5.50

Net Charge (pH 7.4) 5.27

Charge Density (pH 7.0) 0.0510

GRAVY Index0.92

Hydrophobic Moment 0.69

Boman Index0.34

Instability Index22.47

Aliphatic Index 138.33

Aromaticity 0.0648

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4236.66

LogP -29.05

H-bond Donors 147.0

H-bond Acceptors 145.0

Rotatable Bonds 384.0

Heavy Atoms 795.0

Ring Count 10.0

Amide Bonds 113.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0281813 VERIFIED: NO

Provenance & Taxonomy

OrganismPaenibacillus larvae subsp. larvae DSM 25719 [Bacterium]

FamilyBacteriocin

Tax ID697286

Structure & Mods

Confighead-to-tail cyclic peptide [Cyclic]

Chiralitynoncanonical stereochemical modification [Modified]

Other ModsCyclized peptide scaffold annotation

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Non-hemolytic Non-ribosomal

RECORD: Rec_0387377 VERIFIED: NO

Provenance & Taxonomy

OrganismPaenibacillus larvae subsp. larvae [Bacterium]

FamilyCircular bacteriocin

Structure & Mods

Confighead-to-tail cyclic bacteriocin scaffold [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Bacteriocin Non-hemolytic Non-ribosomal