Peptide Database

Peptide NameT-261

Function Ontology

Anticancer

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antiviral

Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition

Antiviral ▸ Antiviral mechanism ▸ Viral fusion inhibition ▸ Fusion inhibitor

Therapeutic / Biomedical activity ▸ Protective bioactivity ▸ Cell protection ▸ Cytoprotection

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length35 amino acids

Chemical FormulaC159H266N42O58

DescriptionStandard

        DLGPPISLERLDVGTNLGNAIAKLEDAKELLESSD
    

Molecular Weight3694.06 Da

Isoelectric Point (pI)4.18

Net Charge (pH 7.0)-5.22

Net Charge (pH 7.4) -5.44

Charge Density (pH 7.0) -0.1492

GRAVY Index-0.27

Hydrophobic Moment 0.54

Boman Index0.02

Instability Index17.73

Aliphatic Index 117.14

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1614.58

LogP -17.09

H-bond Donors 53.0

H-bond Acceptors 53.0

Rotatable Bonds 126.0

Heavy Atoms 259.0

Ring Count 2.0

Amide Bonds 36.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0305648 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermAcetylation

C-TermAmidation

Bio-Activity Profile

Function

Antimicrobial Antiviral

Targetmeasles virus(MV):protection of HEp2 cell from viral cytopathic effect(CPE)

Activity5.7 μg/mL

MethodEC50

RECORD: Rec_0336228 VERIFIED: YES