Peptide Database

Peptide NameEndolysin (EC 3.5.1.28) (N-acetylmuramoyl-L-alanine amidase)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Bacteriolytic activity ▸ Bacteriolytic enzyme

Enzyme / Catalytic activity ▸ Hydrolase

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length152 amino acids

Chemical FormulaC747H1172N216O218S7

DescriptionStandard

        MASKVQFKPRTVTDAIFVHCSATQPSQDIGVDTIRMWHKQQGWLDVGYHFVIKRDGTVESGRPVDVVGSHVKDWNSRSVGVCLVGGIDAKGKFEANFTPAQMSALRNKLAELKVLYPQADIKAHHDVAPKACPSFDLQRWLNTNEMVTSDRG
    

Molecular Weight16891.07 Da

Isoelectric Point (pI)8.83

Net Charge (pH 7.0)3.01

Net Charge (pH 7.4) 2.41

Charge Density (pH 7.0) 0.0198

GRAVY Index-0.35

Hydrophobic Moment 0.58

Boman Index-0.02

Instability Index40.27

Aliphatic Index 76.25

Aromaticity 0.0789

Extinction Coeff. Reduced 24980.00

Extinction Coeff. Oxidized 25105.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6974.12

LogP -71.88

H-bond Donors 243.0

H-bond Acceptors 234.0

Rotatable Bonds 556.0

Heavy Atoms 1188.0

Ring Count 29.0

Amide Bonds 164.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0047266 VERIFIED: NO

Provenance & Taxonomy

OrganismEscherichia phage IMM-002 [Virus]

FamilyN-acetylmuramoyl-L-alanine amidase 2

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Hydrolase Cytolytic Non-hemolytic