Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length114 amino acids

Chemical FormulaC544H881N151O164S3

DescriptionStandard

        PDLTGHEKFGLGNVKYNISRIHVTAVELPSASISLLPGSGIKLVIGNASLTIDMNWNIRTWMFKDSGRGTVHISKVFVTAIFSTPLDNTGPRSISLTSCRTTSGDIDIKLNGKS
    

Molecular Weight12256.92 Da

Isoelectric Point (pI)9.59

Net Charge (pH 7.0)4.21

Net Charge (pH 7.4) 3.97

Charge Density (pH 7.0) 0.0370

GRAVY Index-0.00

Hydrophobic Moment 0.54

Boman Index0.10

Instability Index22.52

Aliphatic Index 96.58

Aromaticity 0.0614

Extinction Coeff. Reduced 12490.00

Extinction Coeff. Oxidized 12490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5037.74

LogP -57.03

H-bond Donors 180.0

H-bond Acceptors 174.0

Rotatable Bonds 406.0

Heavy Atoms 862.0

Ring Count 17.0

Amide Bonds 120.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0164303 VERIFIED: NO

Provenance & Taxonomy

OrganismEulacestoma nigropectus [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria