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MYP_071141
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Basic Information
PSN-PC
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Anti-biofilm ▸ Biofilm inhibition
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
19 amino acids
C95H161N23O22
Standard
Sequence
FLSLIPKIATGIAALAKHL
Physicochemical Analysis
1977.44 Da
10.00
1.85
1.59
0.0971
1.27
0.52
0.47
-5.45
164.74
0.0526
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
699.51
-2.50
24.0
25.0
64.0
140.0
3.0
18.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0008272 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa camba [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
Horse erythrocytes=
50 %
Hemolysis
PaperPubMed PMID: 29112170 PMID29112170 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29112170/
RECORD: Rec_0029742 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Anticancer
RECORD: Rec_0065706 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa camba [Animal]
Phylloseptin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Escherichia coli NCTC 10418
8 μM
MIC
PMID29112170 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29112170/
RECORD: Rec_0074380 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa camba [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
PaperPubMed PMID: 29112170 PMID29112170 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29112170/
RECORD: Rec_0086519 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa camba [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Anticancer
Pseudomonas aeruginosa
32 μM
MIC
PaperPSN-PC: A Novel Antimicrobial and Anti-Biofilm Peptide from the Skin Secretion of Phyllomedusa-camba with Cytotoxicity on Human Lung Cancer Cell
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