Peptide Database

Peptide NameLantibiotic

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Standard StatusStandard

Sequence Length46 amino acids

Chemical FormulaC205H320N54O75S5

DescriptionStandard

        MNNVKNLFDLDVQVTTTSSDVDPQITSVSLCTPGCGDTGSWNSFCC
    

Molecular Weight4901.38 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-4.53

Net Charge (pH 7.4) -4.81

Charge Density (pH 7.0) -0.0986

GRAVY Index-0.05

Hydrophobic Moment 0.44

Boman Index0.10

Instability Index18.12

Aliphatic Index 65.43

Aromaticity 0.0652

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5750.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2084.85

LogP -29.96

H-bond Donors 74.0

H-bond Acceptors 76.0

Rotatable Bonds 155.0

Heavy Atoms 339.0

Ring Count 6.0

Amide Bonds 51.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0106770 VERIFIED: NO

Provenance & Taxonomy

OrganismPriestia megaterium [Animal]

FamilyLantibiotic

Structure & Mods

Configthioether-cyclized lantibiotic scaffold [Cyclic]

Chiralitypost-translationally modified ribosomal peptide [Modified]

Other ModsLanthionine/methyllanthionine-type thioether crosslinks are implied by the lantibiotic annotation

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Lantibiotic Anti-Gram-positive

TargetGram-positive bacteria