Peptide Database

Peptide NameBrevinin-2ISa

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive ▸ Anti-Staphylococcus aureus

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Anti-Candida

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length76 amino acids

Chemical FormulaC363H599N95O119S6

DescriptionStandard

        MFNMKKSLLLLFFLGTISLSLCEEERDADEDDGVEMTEEEVKRSLLDTFKNLAVNAAKSAGVSVLNALSCKISRTC
    

Molecular Weight8390.59 Da

Isoelectric Point (pI)4.68

Net Charge (pH 7.0)-4.51

Net Charge (pH 7.4) -4.79

Charge Density (pH 7.0) -0.0593

GRAVY Index0.05

Hydrophobic Moment 0.71

Boman Index0.02

Instability Index42.55

Aliphatic Index 98.82

Aromaticity 0.0526

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3487.66

LogP -35.46

H-bond Donors 124.0

H-bond Acceptors 121.0

Rotatable Bonds 294.0

Heavy Atoms 583.0

Ring Count 4.0

Amide Bonds 79.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0203909 VERIFIED: YES

Provenance & Taxonomy

OrganismOdorrana ishikawae [Animal]

FamilyBrevinin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-MRSA Antifungal Anti-Candida Anti-Gram-negative Anti-Gram-positive Non-hemolytic

TargetStaphylococcus aureus

RECORD: Rec_0298051 VERIFIED: NO

Provenance & Taxonomy

OrganismOdorrana ishikawae [Animal]

FamilyBrevinin

Structure & Mods

ConfigSingle-chain peptide backbone represented as a linear sequence entry [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial

RECORD: Rec_0320996 VERIFIED: YES

Provenance & Taxonomy

OrganismOdorrana ishikawae [Animal]

FamilyBrevinin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-MRSA Antifungal Anti-Candida Anti-Gram-negative Anti-Gram-positive Non-hemolytic

TargetEscherichia coli

RECORD: Rec_0339334 VERIFIED: YES

Provenance & Taxonomy

OrganismOdorrana ishikawae [Animal]

FamilyBrevinin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-MRSA Antifungal Anti-Candida Anti-Gram-negative Anti-Gram-positive Non-hemolytic

TargetBacillus subtilis