Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length88 amino acids

Chemical FormulaC422H679N117O115S11

DescriptionStandard

        MPGSSGVLPSDLPRSPAAMTQLLLLIVALLALGHMPPGRSEFKRCWKGQGACRTYCTRQEIYMHMCPDASLCCLAYGTRPLASKPVYV
    

Molecular Weight9584.34 Da

Isoelectric Point (pI)9.08

Net Charge (pH 7.0)4.62

Net Charge (pH 7.4) 4.20

Charge Density (pH 7.0) 0.0525

GRAVY Index0.13

Hydrophobic Moment 0.55

Boman Index0.11

Instability Index80.95

Aliphatic Index 84.32

Aromaticity 0.0682

Extinction Coeff. Reduced 11460.00

Extinction Coeff. Oxidized 11835.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3620.44

LogP -33.07

H-bond Donors 132.0

H-bond Acceptors 133.0

Rotatable Bonds 301.0

Heavy Atoms 665.0

Ring Count 18.0

Amide Bonds 90.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0387669 VERIFIED: NO

Provenance & Taxonomy

OrganismCallorhinus ursinus [Animal]

FamilyDefensin

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence