Peptide Database

Peptide NameHepcidin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length89 amino acids

Chemical FormulaC431H696N120O135S8

DescriptionStandard

        MKTFWFAVAVAVVLTSICIQESSAVPGPEVQELEELEEPMSIESLVSDQEEPSEDSWKMPSSIREKRGIKCRFRCSHGVCGLSCKKRRG
    

Molecular Weight9975.38 Da

Isoelectric Point (pI)5.42

Net Charge (pH 7.0)-2.43

Net Charge (pH 7.4) -2.80

Charge Density (pH 7.0) -0.0273

GRAVY Index-0.30

Hydrophobic Moment 0.54

Boman Index-0.06

Instability Index86.75

Aliphatic Index 74.38

Aromaticity 0.0562

Extinction Coeff. Reduced 11000.00

Extinction Coeff. Oxidized 11250.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4102.64

LogP -42.27

H-bond Donors 148.0

H-bond Acceptors 142.0

Rotatable Bonds 337.0

Heavy Atoms 694.0

Ring Count 13.0

Amide Bonds 91.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0140794 VERIFIED: NO

Provenance & Taxonomy

OrganismNotothenia angustata [Animal]

FamilyHepcidin

Tax ID8210

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Non-hemolytic Non-ribosomal

RECORD: Rec_0402800 VERIFIED: NO