Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length394 amino acids

Chemical FormulaC1992H3102N520O550S8

DescriptionStandard

        SFHLPYSRISLVPNVGLQVSISNAFAELDGNWRVKFHFIRDHGSFDLKVDNVYIKINLKLGSDTSGKPTIDTSGCSTHISEVRVHFSGKFGWLYNLFYSAVESRFRKILESKVCESVAKSVHSDLQPYLRTLPVTARIDAVAGIDYSLVAPPRATAQSLDVGLKGEFFSLAHRSTVPFPPLALALPPDHERMVYFGASSYFFNTAAFAYHAAGALVFDITDSMIPKDVEFHLNTSTFSAFVPQLEKMYPEMPMKLRLSAPSAPFLSIGPEGLSLRPVVDIQAYAILPTASLAPLFLLSLVSNVSAVIDVKAGHIVGNLKVGSLKPFSAPSAPQVRTLQSIMNILASSILLPRLNDRLEQGFPLPLPDRIQLSNILVRFHQNFLLLGADVHYQPR
    

Molecular Weight43391.61 Da

Isoelectric Point (pI)8.91

Net Charge (pH 7.0)4.60

Net Charge (pH 7.4) 3.63

Charge Density (pH 7.0) 0.0117

GRAVY Index0.17

Hydrophobic Moment 0.66

Boman Index0.15

Instability Index40.41

Aliphatic Index 102.21

Aromaticity 0.1015

Extinction Coeff. Reduced 28880.00

Extinction Coeff. Oxidized 29005.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0163644 VERIFIED: NO

Provenance & Taxonomy

OrganismBaryphthengus martii [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria