Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length544 amino acids

Chemical FormulaC2575H4120N748O734S16

DescriptionStandard

        MGLGHGDLGEVLVRPAWLPRDGHRRHGALLPLAALGEMMETGPAMGPAAPAPGGTATACHGEDGCPPRGSALALLCLLLLPAACSPATGSSPGIKGRVTQRALEYGRHFGLELLRSQLQKEHELNLQGSYQPPLLGEIQYSVPRIHIQELQMNDSSVGFAEDVGVRLAVQGARIQLSANWSAQLGTFQDSGVVQLRVADLAVAVVLGLSVDEGGRPAVWAAGCDARGTDLHLEFHRGQSWLYNLLVPLFQRTLRQQLNKQLCVELEKSISRMEASLKRMRVSPQLDPFAAIDLSLLGRPDITAEHGDVSLKGEFFGVGRRWQSPFSPKPVGLPEAREPMVLLALTEFVANSAAFVYFTAGALRRNISGEALPRRFPIQLSTKSLGGFSPKLQELFPDLPMELQLSARRQPLLSCHPDALHGTLYGSAEAFVVLPNATRLPVFLLDIDANVTGKPSITGNRLGGTVRLTSLSVAQVTSQVGPLQVAVPPRASPSGGPAAHPPRPQPGAPAPLAARGLPAPRHGPAVRALRPAASSKGTLQGWGAF
    

Molecular Weight57813.87 Da

Isoelectric Point (pI)9.24

Net Charge (pH 7.0)8.72

Net Charge (pH 7.4) 7.62

Charge Density (pH 7.0) 0.0160

GRAVY Index-0.04

Hydrophobic Moment 0.73

Boman Index0.08

Instability Index53.58

Aliphatic Index 94.21

Aromaticity 0.0551

Extinction Coeff. Reduced 41940.00

Extinction Coeff. Oxidized 42315.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0110073 VERIFIED: NO

Provenance & Taxonomy

OrganismAythya fuligula (Tufted duck) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria