Peptide Database

Peptide NameEnkephalin analog

Function Ontology

Neurological / Signaling ▸ Analgesic/opioid activity ▸ Analgesic

Standard StatusStandard

Sequence Length6 amino acids

Chemical FormulaC34H44N8O11

DescriptionStandard

        PFPHED
    

Molecular Weight740.76 Da

Isoelectric Point (pI)4.64

Net Charge (pH 7.0)-1.95

Net Charge (pH 7.4) -2.06

Charge Density (pH 7.0) -0.3245

GRAVY Index-1.77

Hydrophobic Moment 0.08

Boman Index-0.10

Instability Index104.63

Aliphatic Index 0.00

Aromaticity 0.1667

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 289.32

LogP -1.70

H-bond Donors 9.0

H-bond Acceptors 10.0

Rotatable Bonds 19.0

Heavy Atoms 53.0

Ring Count 4.0

Amide Bonds 5.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0051557 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

FamilyEnkephalin

Structure & Mods

Configlinear peptide [Linear]

Chiralitymixed L/D amino-acid peptide [Mixed]

N-TermNone

C-TermHydroxylation

Other ModsPara florination of amino group of phenylalanine

Bio-Activity Profile

Function

Analgesic

MethodHPLC , reverse phase HPLC, Partition coefficient

Half-LifeMouse plasma, in vitro; >18000 s