Peptide Database

Peptide NameEndokinin-2

Function Ontology

Cardiovascular ▸ Vascular tone modulation ▸ Vasoactive peptide

Cardiovascular ▸ Vascular tone modulation ▸ Vasodilatory activity

Neurological / Signaling ▸ Neuromodulation

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Standard StatusStandard

Sequence Length12 amino acids

Chemical FormulaC59H100N20O16S

DescriptionStandard

        VRGYQMGQRGLL
    

Molecular Weight1377.61 Da

Isoelectric Point (pI)10.83

Net Charge (pH 7.0)1.73

Net Charge (pH 7.4) 1.52

Charge Density (pH 7.0) 0.1444

GRAVY Index-0.40

Hydrophobic Moment 0.63

Boman Index-0.10

Instability Index-12.06

Aliphatic Index 89.17

Aromaticity 0.0833

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 613.63

LogP -5.87

H-bond Donors 22.0

H-bond Acceptors 19.0

Rotatable Bonds 47.0

Heavy Atoms 96.0

Ring Count 1.0

Amide Bonds 13.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0049723 VERIFIED: NO

Provenance & Taxonomy

OrganismOryctolagus cuniculus [Animal]

FamilyEndokinin

Tax ID9986

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide Neuromodulator Vasoactive Vasodilator

Half-LifeMammalian: 100 hour; Yeast: >20 hour; E. coli: >10 hour