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MYP_070990
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Basic Information
Catestatin
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Cardiovascular
Hormonal / Endocrine ▸ Hormone peptide
Immunology ▸ Immune cell migration ▸ Chemotactic peptide
Immunology ▸ Immune modulation ▸ Immunomodulatory activity
Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Host defense activity
Membrane / Ion-channel modulation ▸ Calcium channel modulation ▸ Calcium channel inhibitor
Neurological / Signaling ▸ Neuromodulation
Neurological / Signaling ▸ Neuromuscular and muscle activity ▸ Myotropic activity
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Regulatory peptide ▸ Biological modulation
Standard
21 amino acids
C104H164N32O27S
Standard
Sequence
SSMKLSFRARAYGFRGPGPQL
Physicochemical Analysis
2326.68 Da
11.72
3.46
3.25
0.1647
-0.49
0.31
-0.10
15.74
46.67
0.1429
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
963.47
-10.52
35.0
32.0
74.0
164.0
5.0
21.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0127928 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Antioxidant
A. niger
20 μM
MIC
PaperNew antimicrobial activity for the catecholamine release-inhibitory peptide from chromogranin A
RECORD: Rec_0130702 VERIFIED: NO
Provenance & Taxonomy
Homo sapiens [Animal]
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hormone Antimicrobial
Plasmodium falciparum
RECORD: Rec_0157336 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Catestatin
9606
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
2:Phosphoserine; 3:Methionine sulfoxide
Bio-Activity Profile
Antimicrobial Anti-Gram-negative Antibacterial Hormone Endocrine Neuropeptide Neuromodulator Cardiovascular Myotropic Receptor modulation Immunomodulatory
cells and noradrenergic neurons
Mammalian: 1.9 hour; Yeast: >20 hour; E. coli: >10 hour
PaperSource-linked PubMed record(s) for Catestatin (Homo sapiens): PMID 10781584 PMID10781584 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10781584/
RECORD: Rec_0173450 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
9913
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PaperPubMed PMID: 15723172 PMID15723172 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15723172/
RECORD: Rec_0208414 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
Candida albicans
240 μg/mL
MIC
PMID35216181 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35216181/
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