Peptide Database

Peptide NameBeta-defensin 105 (Beta-defensin 5) (BD-5) (DEFB-5) (Defensin; beta 105)

Function Ontology

Antimicrobial

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length78 amino acids

Chemical FormulaC397H620N108O106S10

DescriptionStandard

        MALIRKTFYFLFAMFFILVQLPSGCQAGLDFSQPFPSGEFAVCESCKLGRGKCRKECLENEKPDGNCRLNFLCCRQRI
    

Molecular Weight8922.48 Da

Isoelectric Point (pI)8.71

Net Charge (pH 7.0)3.43

Net Charge (pH 7.4) 3.08

Charge Density (pH 7.0) 0.0440

GRAVY Index0.04

Hydrophobic Moment 0.46

Boman Index0.02

Instability Index42.71

Aliphatic Index 72.56

Aromaticity 0.1282

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1990.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3454.47

LogP -29.90

H-bond Donors 126.0

H-bond Acceptors 120.0

Rotatable Bonds 297.0

Heavy Atoms 621.0

Ring Count 14.0

Amide Bonds 84.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0213177 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyBeta-defensin; Defensin

Tax ID9606

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidedisulfide bond; sites not specified

Bio-Activity Profile

Function

Antimicrobial Defensin Non-hemolytic

RECORD: Rec_0274737 VERIFIED: NO

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyDefensin

Tax ID32630

Structure & Mods

ConfigSingle-chain peptide backbone represented as a linear sequence entry [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial