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MYP_070961
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Basic Information
Unnamed
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
17 amino acids
C99H154N34O20S4
Standard
Sequence
RWCFRVCYRGICYRKCR
Physicochemical Analysis
2268.76 Da
9.93
5.72
5.45
0.3363
-0.52
0.72
-0.44
13.22
40.00
0.2353
8480.00
8730.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
920.69
-6.48
41.0
30.0
72.0
157.0
5.0
16.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0367919 VERIFIED: YES
Provenance & Taxonomy
Limulus polyphemus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus 209P
0.5 μM
MIC
PMID30486233 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30486233/
RECORD: Rec_0374119 VERIFIED: YES
Provenance & Taxonomy
Tachypleus tridentatus [Animal]
Tachyplesin
Structure & Mods
head-to-tail cyclic peptide [Cyclic]
noncanonical stereochemical modification [Modified]
Bio-Activity Profile
Antimicrobial Antifungal
S. typhimurium LT2 or 1102
1.6-3.1 μg/mL
MIC
PaperAntimicrobial peptides, isolated from horseshoe crab hemocytes, tachyplesin II, and polyphemusins I and II: chemical structures and biological activity.
RECORD: Rec_0385374 VERIFIED: YES
Provenance & Taxonomy
Tachypleus tridentatus [Animal]
Tachyplesin
Structure & Mods
head-to-tail cyclic peptide [Cyclic]
noncanonical stereochemical modification [Modified]
Bio-Activity Profile
Antimicrobial Antifungal
Escherichia coli K12
3.1 μg/mL
MIC
PaperAntimicrobial peptides, isolated from horseshoe crab hemocytes, tachyplesin II, and polyphemusins I and II: chemical structures and biological activity.
RECORD: Rec_0400829 VERIFIED: YES
Provenance & Taxonomy
Arthropoda [Animal]
6656
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Hydroxyproline-like notation
Bio-Activity Profile
Antimicrobial
PMID3141410 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/3141410/
RECORD: Rec_0408125 VERIFIED: YES
Provenance & Taxonomy
Limulus polyphemus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Klebsiella pneumoniae
1 μM
MIC
PMID30486233 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30486233/
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