Peptide Database

Peptide NameEndolysin (EC 3.5.1.28) (N-acetylmuramoyl-L-alanine amidase)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Bacteriolytic activity ▸ Bacteriolytic enzyme

Enzyme / Catalytic activity ▸ Hydrolase

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length151 amino acids

Chemical FormulaC754H1179N219O217S5

DescriptionStandard

        MAKVQFKPRETTEAIFVHCSATKPSQNIGVREIRQWHKEQGWLDVGYHFIIKRDGTVEAGRDELAVGSHVKGYNHNSVGVCLVGGIDDKGKFDANFTPAQMQALRSLLVTLLAKYEGSVLRAHHDVAPKACPSFDLKRWWEKNELVTSDRG
    

Molecular Weight16944.09 Da

Isoelectric Point (pI)8.79

Net Charge (pH 7.0)3.10

Net Charge (pH 7.4) 2.44

Charge Density (pH 7.0) 0.0205

GRAVY Index-0.44

Hydrophobic Moment 0.75

Boman Index-0.04

Instability Index36.74

Aliphatic Index 78.74

Aromaticity 0.0861

Extinction Coeff. Reduced 26470.00

Extinction Coeff. Oxidized 26595.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7027.16

LogP -68.14

H-bond Donors 247.0

H-bond Acceptors 232.0

Rotatable Bonds 565.0

Heavy Atoms 1195.0

Ring Count 29.0

Amide Bonds 161.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0020478 VERIFIED: NO

Provenance & Taxonomy

OrganismSerratia phage SM9-3Y [Virus]

FamilyN-acetylmuramoyl-L-alanine amidase 2

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Hydrolase Cytolytic Non-hemolytic

RECORD: Rec_0202085 VERIFIED: YES