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MYP_070911
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Basic Information
M-oxotoxin-Ot1a (Oxyopinin-1, Oxki1; spiders, Arthropods, animals)
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Insecticidal/Pest control ▸ Insecticidal activity
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity
Venom / Toxin ▸ General toxin ▸ Toxic
Venom / Toxin ▸ General toxin ▸ Toxin
Standard
48 amino acids
C235H409N71O60S
Standard
Sequence
FRGLAKLLKIGLKSFARVLKKVLPKAAKAGKALAKSMADENAIRQQNQ
Physicochemical Analysis
5221.27 Da
11.26
9.76
9.54
0.2032
-0.20
0.90
-0.10
6.91
103.96
0.0417
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
2172.62
-19.45
75.0
71.0
189.0
367.0
3.0
52.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0257473 VERIFIED: NO
Provenance & Taxonomy
Oxyopes kitabensis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Insecticidal
Escherichia coli, Bacillus subtilis and, Staphylococcus aureus an hemolytic
RECORD: Rec_0265555 VERIFIED: YES
Provenance & Taxonomy
Oxyopes takobius [Animal]
Cationic peptide 02 (oxyopinin-2)
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Anti-Gram-negative Anti-Gram-positive Cytolytic Toxin Hemolytic Insecticidal
Escherichia coli
PMID11976325;15328050 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11976325/
RECORD: Rec_0281990 VERIFIED: YES
Provenance & Taxonomy
Oxyopes takobius [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Insecticidal
Staphylococcus aureus
6.2 μM
MIC
PMID11976325;15328050 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11976325/
RECORD: Rec_0282020 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial
Guinea-pig erythrocytes
6 μM
Hemolysis
Paperhttps://pubmed.ncbi.nlm.nih.gov/15328050/ PMID15328050 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15328050/
RECORD: Rec_0289500 VERIFIED: YES
Provenance & Taxonomy
Oxyopes takobius [Animal]
Cationic peptide 02 (oxyopinin-2)
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Anti-Gram-negative Anti-Gram-positive Cytolytic Toxin Hemolytic Insecticidal
Bacillus subtilis
PMID11976325;15328050 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11976325/
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