Peptide Database

Peptide NameMolt-inhibiting hormone

Function Ontology

Developmental biology ▸ Molting regulation

Hormonal / Endocrine ▸ Hormone peptide

Neurological / Signaling ▸ Neuromodulation

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Standard StatusStandard

Sequence Length78 amino acids

Chemical FormulaC400H618N116O120S8

DescriptionStandard

        RVINDDCPNLIGNRDLYKRVEWICEDCSNIFRNTGMATLCRKNCFFNEDFLWCVYATERTEEMSQLRQWVGILGAGRE
    

Molecular Weight9228.41 Da

Isoelectric Point (pI)5.10

Net Charge (pH 7.0)-2.27

Net Charge (pH 7.4) -2.59

Charge Density (pH 7.0) -0.0291

GRAVY Index-0.42

Hydrophobic Moment 0.65

Boman Index-0.10

Instability Index48.14

Aliphatic Index 73.72

Aromaticity 0.1154

Extinction Coeff. Reduced 19480.00

Extinction Coeff. Oxidized 19855.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3887.09

LogP -37.34

H-bond Donors 142.0

H-bond Acceptors 126.0

Rotatable Bonds 307.0

Heavy Atoms 644.0

Ring Count 13.0

Amide Bonds 86.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0040220 VERIFIED: NO

Provenance & Taxonomy

OrganismMetacarcinus magister [Animal]

FamilyArthropod CHH/MIH/GIH/VIH hormone

Tax ID29965

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide Arthropod neurohormone

RECORD: Rec_0093465 VERIFIED: YES

Provenance & Taxonomy

OrganismMetacarcinus magister [Animal]

FamilyMolt-inhibiting hormone

Tax ID29965

Structure & Mods

Configdisulfide-constrained peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide7-44; 24-40; 27-53

Bio-Activity Profile

Function

Hormone Endocrine Neuropeptide Neuromodulator Molting regulator

Half-LifeMammalian: 1 hour; Yeast: 2 min; E. coli: 2 min

RECORD: Rec_0279039 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/