Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length369 amino acids

Chemical FormulaC1875H3032N492O525S17

DescriptionStandard

        MKSCVVIFFLVSLISSDTAAPPPGIKVRITEKVKDLGLMYLKGLVNREFLIENEDFLIKSVTLTKLQIDPAQVDFRFQDKIGLQFEIRDLNFALQLQREKNVQFFKKFKIDKGTTIFTGEGVRAMILVRMNQNPKGHLNVEIGKEDCKINADSIRTKSTGFVGKVLDKFKSLTKHFFKKKICPALQPMINDKLKDLSTMRTVHEGRQLDLDYSLSSDIAVTSRSLDMSFKGLMSVRGQAVDTDSIRPGKEPVFTETNKMIYVGISEFFFNGAAMAIYKSGPFEVNVPKLEGLKSVVNLLLGAVGIQPGPWTAELTEAPIIQISKAGLSATVNFKAQPKAKQKGFLMTCKVDMNVEFKERHLTMKFKLPK
    

Molecular Weight41412.22 Da

Isoelectric Point (pI)9.58

Net Charge (pH 7.0)16.84

Net Charge (pH 7.4) 16.25

Charge Density (pH 7.0) 0.0456

GRAVY Index-0.11

Hydrophobic Moment 0.63

Boman Index0.03

Instability Index20.31

Aliphatic Index 92.68

Aromaticity 0.0840

Extinction Coeff. Reduced 11460.00

Extinction Coeff. Oxidized 11710.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0146077 VERIFIED: NO

Provenance & Taxonomy

OrganismOreochromis niloticus (Not founde tilapia) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria