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MYP_070825
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Basic Information
Unnamed
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
6 amino acids
C30H60N12O7S2
Standard
Sequence
CRKKKC
Physicochemical Analysis
765.00 Da
9.85
3.74
3.50
0.6229
-1.87
0.24
-1.07
8.33
0.00
0.0000
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
348.78
-3.67
15.0
13.0
29.0
51.0
0.0
5.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0170387 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
cyclic/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
Fatty acylation (palmitic acid)
Amidation
Bio-Activity Profile
Antimicrobial Anticancer
HeLa
38.8±4.4 μg/mL
IC50
PaperPubMed PMID: 33003569 PMID33003569 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33003569/
RECORD: Rec_0175536 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Staphylococcus aureus
PMID28767074;33003569 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28767074/
RECORD: Rec_0187249 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
cyclic/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
Fatty acylation (palmitic acid)
Amidation
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
Human erythrocytes
66
HC50
PaperPubMed PMID: 33003569 PMID33003569 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33003569/
RECORD: Rec_0190380 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
Human erythrocytes (50% Hemolysis at 66.5+-14.8 microg/ml, Human keratinocytes HaCat (IC50 at 36.8+-2.7 microg/ml
14.8 μg/mL
Hemolysis
PMID28767074;33003569 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28767074/
RECORD: Rec_0205709 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Yarrowia lipolytica PCM 2680-FY
4 μg/mL
MIC
PMID28767074;33003569 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28767074/
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