Peptide Database

Peptide NameSLAY-screened peptide P12

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length8 amino acids

Chemical FormulaC43H74N10O10

DescriptionStandard

        HLLPVISI
    

Molecular Weight891.11 Da

Isoelectric Point (pI)6.74

Net Charge (pH 7.0)-0.15

Net Charge (pH 7.4) -0.41

Charge Density (pH 7.0) -0.0191

GRAVY Index1.90

Hydrophobic Moment 0.23

Boman Index0.69

Instability Index56.90

Aliphatic Index 231.25

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 307.14

LogP 0.10

H-bond Donors 10.0

H-bond Acceptors 11.0

Rotatable Bonds 26.0

Heavy Atoms 63.0

Ring Count 2.0

Amide Bonds 7.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0076061 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/