Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length156 amino acids

Chemical FormulaC778H1255N209O237S14

DescriptionStandard

        MNLLILTFIICGLLTQVTKGSFEPQKCWKNNIGYCRRRCLDTERYILLCRNKLSCCISIIISYEYTRRPPFRVIHLEDITFDYSDMGSFTGSPVSKLSDLVTFDIRRETMTPKTNTPETTMPPSETTTSKTTMPSSKTTTSKTTMPPPSQMALTHN
    

Molecular Weight17777.46 Da

Isoelectric Point (pI)9.03

Net Charge (pH 7.0)5.62

Net Charge (pH 7.4) 5.16

Charge Density (pH 7.0) 0.0360

GRAVY Index-0.33

Hydrophobic Moment 0.60

Boman Index-0.04

Instability Index68.54

Aliphatic Index 70.58

Aromaticity 0.0769

Extinction Coeff. Reduced 12950.00

Extinction Coeff. Oxidized 13325.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7177.73

LogP -78.65

H-bond Donors 261.0

H-bond Acceptors 259.0

Rotatable Bonds 579.0

Heavy Atoms 1238.0

Ring Count 27.0

Amide Bonds 164.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0068220 VERIFIED: NO

Provenance & Taxonomy

OrganismMacaca mulatta [Animal]

FamilyDefensin

Tax ID9544

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence

RECORD: Rec_0366381 VERIFIED: NO