Peptide Database

Peptide NameCecropin-P4

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length74 amino acids

Chemical FormulaC372H610N106O112S2

DescriptionStandard

        MFLMYLLVQTTESSWLSKTYKKLENSAKKRISEGVAIAILGGLRHRRSVAHQEEASLHVKTDELPSPDTVREQL
    

Molecular Weight8423.60 Da

Isoelectric Point (pI)9.16

Net Charge (pH 7.0)1.78

Net Charge (pH 7.4) 1.38

Charge Density (pH 7.0) 0.0240

GRAVY Index-0.41

Hydrophobic Moment 0.59

Boman Index-0.08

Instability Index67.72

Aliphatic Index 94.86

Aromaticity 0.0541

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8480.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3549.00

LogP -34.45

H-bond Donors 126.0

H-bond Acceptors 119.0

Rotatable Bonds 289.0

Heavy Atoms 592.0

Ring Count 10.0

Amide Bonds 77.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0021089 VERIFIED: YES

Provenance & Taxonomy

OrganismAscaris suum [Animal]

FamilyCecropin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Anti-Gram-positive Non-hemolytic

TargetGram-negative and Gram-positive bacteria