Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length272 amino acids

Chemical FormulaC1338H2073N329O374S11

DescriptionStandard

        MTFPKIDAVAGVDYSLVGPPTATTQSLDVPMKGECYSLAQRSAVPFSPLALTLPPDHDRMVYFGVSSYFFNTASVAYHEAGALVFEITDSMIPKTIDFHLKTTTFSAFVPQVKKYPDMQMKLRLSAPSAPFLNIGPGGLSLRPVVDIQAYAILPNASMAPLFLLSLVSLGTACSNDSGSRWAAPGAFTALADVVWLVSSPLSLAQRSAVPFSPLALGQGFPLPLLDRIQLSDILVQFHQVSVGSPQPWPEPILFPPEPSAREAACLLLLAPC
    

Molecular Weight29104.47 Da

Isoelectric Point (pI)5.48

Net Charge (pH 7.0)-4.17

Net Charge (pH 7.4) -4.69

Charge Density (pH 7.0) -0.0153

GRAVY Index0.35

Hydrophobic Moment 0.48

Boman Index0.24

Instability Index55.51

Aliphatic Index 97.94

Aromaticity 0.0956

Extinction Coeff. Reduced 26930.00

Extinction Coeff. Oxidized 27180.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0167667 VERIFIED: NO

Provenance & Taxonomy

OrganismCalidris pygmaea [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria