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MYP_070803
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Basic Information
536_1
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
14 amino acids
C84H143N29O15S2
Standard
Sequence
RWRLVCFLCRRKKV
Physicochemical Analysis
1863.35 Da
11.56
5.74
5.50
0.4099
-0.21
0.49
-0.45
85.05
97.14
0.1429
5500.00
5625.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
757.05
-3.76
32.0
23.0
63.0
130.0
3.0
13.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0072283 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
C. trachomatis D/UW-3/Cx MIC90 = 6.3 microM
PMID31302447 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31302447/
RECORD: Rec_0083011 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
Human RBC Lyse approximately 30% of erythrocytes at a concentration of 100 microM
100 μM
Hemolysis
PMID31302447 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31302447/
RECORD: Rec_0108709 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Bacillus subtilis 168 HT
8.6 μM
MIC
PMID31302447 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31302447/
RECORD: Rec_0160024 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli MG1655
17.2 μM
MIC
PMID31302447 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31302447/
RECORD: Rec_0165106 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
6-9
Bio-Activity Profile
Antimicrobial
Escherichia coli MG1655
17.2 μM
MIC
PaperMedicinal leech antimicrobial peptides lacking toxicity represent a promising alternative strategy to combat antibiotic-resistant pathogens
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