Peptide Database

Peptide Namenatriuretic peptide HsNP-a

Function Ontology

Antimicrobial

Cardiovascular

Cardiovascular ▸ Vascular tone modulation ▸ Vasoactive peptide

Cardiovascular ▸ Vascular tone modulation ▸ Vasodilatory activity

Hormonal / Endocrine ▸ Hormone peptide

Regulatory peptide ▸ Biological modulation

Regulatory peptide ▸ Biological regulation

Standard StatusStandard

Sequence Length39 amino acids

Chemical FormulaC153H256N48O52S3

DescriptionStandard

        SGSKTAKIGDGCFGVRLDRIGSTSGMGCGGVPKPTPGGS
    

Molecular Weight3696.15 Da

Isoelectric Point (pI)9.38

Net Charge (pH 7.0)2.44

Net Charge (pH 7.4) 2.20

Charge Density (pH 7.0) 0.0626

GRAVY Index-0.26

Hydrophobic Moment 0.51

Boman Index0.06

Instability Index14.97

Aliphatic Index 47.44

Aromaticity 0.0256

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1581.05

LogP -25.42

H-bond Donors 58.0

H-bond Acceptors 58.0

Rotatable Bonds 121.0

Heavy Atoms 256.0

Ring Count 4.0

Amide Bonds 38.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0083354 VERIFIED: YES

Provenance & Taxonomy

OrganismHoplocephalus stephensii [Animal]

Familynatriuretic peptide HsNP

Tax ID196418

Structure & Mods

Configlinear peptide with reported disulfide constraint [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide12-28

Bio-Activity Profile

Function

Hormone Endocrine Vasoactive Vasodilator Cardiovascular Metabolic regulation Physiological regulation Receptor modulation

Half-LifeMammalian: 1.9 hour; Yeast: >20 hour; E. coli: >10 hour

RECORD: Rec_0235566 VERIFIED: NO