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MYP_070658
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Basic Information
Nigrocin-OG5 (Frogs, amphibians, animals)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Immunology ▸ Adverse immune reactivity ▸ Histamine-release modulation
Immunology ▸ Innate immune modulation ▸ Mast cell modulation
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
21 amino acids
C85H152N24O25S2
Standard
Sequence
GLLSGILGAGKQKVCGLSGLC
Physicochemical Analysis
1974.39 Da
8.90
1.74
1.50
0.0828
0.91
0.40
0.36
13.78
130.00
0.0000
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
780.91
-8.80
29.0
29.0
69.0
136.0
0.0
21.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0057321 VERIFIED: YES
Provenance & Taxonomy
Odorrana grahami [Animal]
Nigrocin
167935
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
15-21
Bio-Activity Profile
Antimicrobial Antifungal
Bacillus subtilis
37.5 μg/mL
MIC
PaperAnti-infection peptidomics of amphibian skin PMID17272268 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17272268/
RECORD: Rec_0064311 VERIFIED: NO
Provenance & Taxonomy
Rana grahami,Huia grahami [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
RECORD: Rec_0081086 VERIFIED: YES
Provenance & Taxonomy
Odorrana grahami [Animal]
Nigrocin
167935
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus
18.75 μg/mL
MIC
PMID17272268 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17272268/
RECORD: Rec_0151311 VERIFIED: YES
Provenance & Taxonomy
Odorrana grahami [Animal]
Nigrocin
167935
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Bacillus subtilis
37.50 μg/mL
MIC
PMID17272268 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17272268/
RECORD: Rec_0171448 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 0.0%, E 9.5%, T 52.4%, C 38.1% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antibacterial Toxic Antimicrobial Antifungal Hemolytic
PaperDADP: the database of anuran defense peptides PMID22467909 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22467909/
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