Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length482 amino acids

Chemical FormulaC2422H3840N618O702S21

DescriptionStandard

        MYRENAGISIRGVGGAAGVSANVSRTSTATGFWLRMKSCVLFFFFFYLASPISSITAPPPPGIKLQIRENAKDVLKDLGLMYLKGLVNKQFPIDDICLPIKSVNLTDLQVDPAKVDFKFQENIGVQIEIKDMNFSLEIQREAKVPFTQIKIIEGTTTLTAEGVTATITVRMNQNPQGHLNVEIPRDNCTIKADTIRTTSSGLTGFLLDSLQYFRLYLYLFNDKICPALQPMINNKLKDLPMMSTVYEDHQLDLDYSLSSDIEVTSSSLDISFKGLLSVHGKAVDPGSIRPGREPVFTETNKMVYVGISEFFFNGAAMAIYKSGPFEFNVPEMEGLLVGLGQKIMEIKPGPWTAELIEAPIIEISNDDLSATAYFKAQRKAKLNGFLMTCRFKMDIEFKERLLIMNIQEPKCKEKAGKIKGKFLAFLVNVFHERITKSLVKEIPIPLPAELSLINATNQFEEGYLVVGGSLTFNPQNSSNAGG
    

Molecular Weight53521.48 Da

Isoelectric Point (pI)6.50

Net Charge (pH 7.0)-1.15

Net Charge (pH 7.4) -1.79

Charge Density (pH 7.0) -0.0024

GRAVY Index-0.02

Hydrophobic Moment 0.75

Boman Index0.10

Instability Index32.77

Aliphatic Index 94.88

Aromaticity 0.0913

Extinction Coeff. Reduced 28880.00

Extinction Coeff. Oxidized 29255.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0106994 VERIFIED: NO

Provenance & Taxonomy

OrganismOreochromis niloticus (Not founde tilapia) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria