Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length244 amino acids

Chemical FormulaC1194H1827N329O340S7

DescriptionStandard

        SAQIDPFAAIDYSLVNKPVIAREHGDMDLKGEFYGVGKHRESPFSPAPFLLPDEGDHMLLLGLSEFSANSAAFVYFTAGTLRKNFRDDMVRRWGSQRCRTREGPLCFLGGSSGEPPPLPDLAKQLPAFVVLPNATLASAFLLDLVSAGHSPGPIRLASWIPLSEGPRRMGAGLGYVPARGPLPREVLSPGVYSPAPIWDLYPSRTPPPQGLRSQPWGSHPSWEPHSSPPSEKPNSEPSQPRCVS
    

Molecular Weight26454.74 Da

Isoelectric Point (pI)6.99

Net Charge (pH 7.0)-0.01

Net Charge (pH 7.4) -0.61

Charge Density (pH 7.0) -0.0001

GRAVY Index-0.34

Hydrophobic Moment 0.52

Boman Index0.04

Instability Index59.23

Aliphatic Index 73.20

Aromaticity 0.0902

Extinction Coeff. Reduced 36440.00

Extinction Coeff. Oxidized 36565.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0224726 VERIFIED: NO

Provenance & Taxonomy

OrganismTerrapene carolina triunguis [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria